Our Uncle Sam became more and more hostile to family and friends and no one knew why.
Since most of his hostility was irrational, we figured he was losing his mind because of his age. We laughed at his outbursts and talked about getting him checked out by professionals.
Then, after he committed suicide, we found out how much debt he was in. Only then, when the family was completely ruined, did we acknowledge all the signs of his disease.